Popa-Cherecheanu A, Schmidl D, Werkmeister RM, Chua J, Garhöfer G, Schmetterer L. The use of laser Doppler flowmetry to evaluate oral soft tissue blood flow in humans: A review. Kouadio AA, Jordana F, Koffi NJ, Le Bars P, Soueidan A. Inter-device reproducibility of retrobulbar blood flow velocity measurements in healthy subjects using color Doppler imaging. Verticchio Vercellin AC, Cutolo CA, Dellafiore C, Lava M, Tinelli C, De Silvestri A, et al. Assessment of flow dynamics in retinal and choroidal microcirculation. Wei X, Balne PK, Meissner KE, Barathi VA, Schmetterer L, Agrawal R. Blood flow mechanics and oxygen transport and delivery in the retinal microcirculation: multiscale mathematical modeling and numerical simulation. Further studies are needed to better explain the possible role of HGT in the characterization of the pathophysiology of ocular diseases associated with abnormalities of the vascular function such as glaucoma, age-related macular degeneration, and diabetic retinopathy.įunk RH. Moreover, it produced a significant redistribution of CT. OCTA acquisitions did not show changes in the vascular density of both the superficial retinal layer and deep retinal layer.Ĭonclusions:We demonstrated that HGT-induced exercise can moderately elevate blood pressure without detectable effects on OCTA-derived parameters in healthy young subjects. Instead, a significant redistribution of choroidal thickness (CT) was observed in the macular region, with a significant reduction (-6.5%, p = 0.001) in the outer-nasal macular sector after exercise. OCT structural parameters of the optic nerve did not change significantly. While both diastolic and systolic blood pressures increased significantly aft er exercise ( p < 0.001 and p = 0.003, respectively), the heart rate did not show a significant increment ( p = 0.182). Results:The mean patient age was 34.0 (± 15.2) years.
Blood pressure, heart rate, OCT and OCTA structural and vascular changes were measured and analyzed before and after the HGT-induced exercise. Cardiovascular changes were investigated by performing a practical hand-grip test (HGT). Methods: Twenty one eyes of 21 healthy subjects were analyzed using a swept-source device, including OCT and OCTA acquisitions. Purpose: To examine the relationship between the cardiovascular status and variations in optical coherence tomography (OCT)-derived parameters of the peripapillary and macular tissues, and macular vascular flow area measured by optical coherence tomography angiography (OCTA) in healthy subjects.ĭesign:Prospective, open-label, non-randomized clinical study.
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